Masato Komai Selected Research

4- ((5- (2,4- dichlorobenzylureido)pentyl)(1- (4- chlorophenyl)ethyl)amino)butanoic acid

1/2010

A novel CC-chemokine receptor 3 antagonist, Ki19003, inhibits airway eosinophilia and subepithelial/peribronchial fibrosis induced by repeated antigen challenge in mice.

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Masato Komai Research Topics

Disease

5	Asthma (Bronchial Asthma) 01/2010 - 03/2003
4	Fibrosis (Cirrhosis) 01/2010 - 03/2003
4	Airway Remodeling 01/2010 - 03/2003
3	Inflammation (Inflammations) 01/2009 - 09/2003
2	Alzheimer Disease (Alzheimer's Disease) 03/2022 - 01/2018
2	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 01/2020
2	Eosinophilia 01/2010 - 01/2009
2	Hyperplasia 09/2003 - 03/2003
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2020
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2020
1	Brain Diseases (Brain Disorder) 01/2018
1	Hypersensitivity (Allergy) 06/2008
1	Rhinitis 06/2008
1	Respiratory Hypersensitivity 02/2004
1	Body Weight (Weight, Body) 02/2004

Drug/Important Bio-Agent (IBA)

4	AllergensIBA 01/2010 - 03/2003
2	AntigensIBA 01/2010 - 02/2004
2	CytokinesIBA 01/2009 - 09/2003
2	OvalbuminIBA 01/2009 - 07/2004
1	LipidsIBA 03/2022
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2022
1	Interferon Type IIBA 01/2020
1	Amyloid (Amyloid Fibrils)IBA 01/2018
1	Proteins (Proteins, Gene)FDA Link 01/2018
1	CCR3 ReceptorsIBA 01/2010
1	Butyric Acid (Butanoic Acid)IBA 01/2010
1	4- ((5- (2,4- dichlorobenzylureido)pentyl)(1- (4- chlorophenyl)ethyl)amino)butanoic acidIBA 01/2010
1	pyrimidineIBA 01/2009
1	Anti-Asthmatic Agents (Antiasthmatic Drugs)IBA 01/2009
1	Nerve Growth Factor (NGF)IBA 06/2008
1	Olopatadine Hydrochloride (Patanol)FDA Link 06/2008
1	Pharmaceutical PreparationsIBA 06/2008
1	Histamine (Histamine Dihydrochloride)FDA Link 06/2008
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2008
1	AerosolsIBA 07/2004
1	Interleukin-5 (Interleukin 5)IBA 07/2004
1	Transforming Growth Factor beta (TGF-beta)IBA 07/2004
1	Transforming Growth Factor beta1 (TGF beta 1)IBA 07/2004
1	InterleukinsIBA 07/2004
1	Interleukin-5 Receptors (Interleukin 5 Receptor)IBA 07/2004
1	Prednisolone (Predate)FDA LinkGeneric 02/2004
1	Acetylcholine (Acetylcholine Chloride)FDA Link 02/2004
1	Folic Acid AntagonistsIBA 02/2004
1	N- (1- ((2,4- diamino- 6- pteridinyl)methyl)- 3,4- dihydro - 2H- 1,4- benzothiazine- 7- carbonyl)- L- 2- aminoadipic acidIBA 02/2004
1	Methotrexate (Mexate)FDA LinkGeneric 02/2004
1	ProstaglandinsIBA 09/2003
1	Immunoglobulin E (IgE)IBA 09/2003
1	Epoprostenol (Prostacyclin)FDA LinkGeneric 09/2003
1	Monoclonal AntibodiesIBA 03/2003
1	Interleukin-4 (Interleukin 4)IBA 03/2003

Therapy/Procedure

1	Therapeutics 01/2022
1	Aftercare (After-Treatment) 06/2008
1	Intraperitoneal Injections 07/2004
1	Oral Administration 02/2004